HORDB

ID: hor002357
Uniprot ID: P15513
Protein name: Myomodulin-A
Gene name: MYOMOD1
Organism: Aplysia californica (California sea hare)
Family: Myomodulin family
Source: Animal
Expression: Expressed in all ganglia of the CNS, but only in a subset of neurons including L10 in the abdominal ganglion and B16 in the buccal ganglion.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: PMSMLRL
Length: 7(250-256)
Propeptide: MQVYMLLPLAVFASLTYQGACEETAAAQTSSDASTSSASSEHAENELSRAKRGSYRMMRLGRGLHMLRLGKRGGPVEPESEENLETLLNLLQGYYSDVPEYPSEFDDTDLAYPYEEYDAPAHPRYRRSTPPTDGVVAPDVLQKGSSEFEDFGDSQLDESDEGYYGYDPENYLYGDFEDYLEPEEGGLGEEKRSLSMLRLGKRGLSMLRLGKREGEEGDEMDKKQDESLNDDFENDDIKRTLSMLRLGKRPMSMLR
Signal peptide: MQVYMLLPLAVFASLTYQ
Modification: T7 Leucine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002357_AF2.pdb

hor002357_ESM.pdb

Mass:	95430	Formula:	C36H66N10O9S2
Absent amino acids:	ACDEFGHIKNQTVWY	Common amino acids:	LM
pI:	10.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	64.29	Boman Index:	-378
Half-Life:	>20 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	?	Aliphatic Index	111.43
Instability Index:	8808.57	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 3474664
Title: Myomodulin: A Bioactive Neuropeptide Present in an Identified Cholinergic Buccal Motor Neuron of Aplysia